Virtual Slide List

Resources

Access to the supplemental resources for this session is password-protected and restricted to University of Michigan students. If you are a University of Michigan student enrolled in a histology course at the University of Michigan, please click on the following link and use your Kerberos-password for access to download lecture handouts and the other resources.

Resources on M+Box

This collection was originally compiled by Kent Christensen, Ph.D., J. Matthew Velkey, Ph.D., Lloyd M. Stoolman, M.D., Laura Hessler, and Diedra Mosley-Brower. Currently, it is curated by Michael Hortsch, Ph.D. If you have questions or comments regarding the University of Michigan virtual slide collection, please contact Dr. Hortsch at hortsch at umich.edu.

Virtual Slide List for Histology Course

Search Description
Blood and Bone Marrow
045
Intervertebral disc, H&E, 40X (bone marrow in spongy bone of vertebrae)
048
Fetal leg, cross section, H&E, 40X (bone marrow in tibia and fibula, developing blood cells, sinusoids, megakaryocytes).
050
Decalcified bone, spider monkey, H&E, 40X
081-2
Human blood smear, Giemsa stain, 40X (red blood cell, neutrophil, lymphocytes, monocytes, eosinophils, basophil, platelet).
081-3
Human blood smear, Giemsa stain, 40X (red blood cell, neutrophil, lymphocyte, monocyte, eosinophil, basophil, platelet).
081-4
Human blood smear, Giemsa stain, 40X (red blood cell, neutrophil, lymphocyte, monocyte, eosinophil, basophil, platelet).
63x smear
Human blood smear, Giemsa stain, 63x scan from hematopathology normals collection
86x smear
Human blood smear, Giemsa stain, 86x scan from hematopathology normals collection
UCSF 81
Vertebrae, 7 mo. fetus, trichrome stain, 40X
UCSF 83
Knee joint, 4.5 mo. fetus, trichrome stain, 40X
UCSF 95
Tibia (broken), rat, trichrome stain, 40X
122
Erythrocytes (RBC): RBCs are cut in several planes of section in this micrograph. Why does the one sectioned in the equatorial plane appear to have a large hole in the middle? Note that in contrast to the lymphocyte, neither the two platelets nor the RBCs contain nuclei. The plasma has a flocculent appearance, because the protein concentration is high and has been precipitated by the fixative.
125
Thrombocyte: The thrombocytes or platelets are enucleate cell fragments, which originate from megakaryocytes.
126
Neutrophil: Remember the multi-lobed nucleus and the abundance of dense heterochromatin that you saw in the blood smear. The cytoplasm contains both azurophilic and specific granules. The distinction between these two granule populations is not very clear in this micrograph and you are not responsible for recognizing granule types.
128
Monocyte: Monocytes have a single population of azurophilic granules, which are primary lysosomes.
129
Lymphocyte: Note the small amount of cytoplasm and sparse organelles (except ribosomes).
130
Eosinophil: The bi-lobed nucleus, in combination with the specific granules that contain crystalloids, make it possible to identify this cell as an eosinophil.
131
Basophil: Note that the granules are true secretory granules, discharged by exocytosis. The nucleus is oval or kidney-shaped.
132
Process of Diapedesis/Extravasation.
139
Erythroblast (nuclear extrusion): When the nucleus becomes extruded during maturation of an erythrocyte, the cell becomes a reticulocyte, which is a nearly mature erythrocyte. The reticulocytes are normally found in the bone marrow (except about 1%) and still have some cellular organelles, such as mitochondria, Golgi vesicles and polysomes. This gives the cytoplasm a basophilic character.
Cardiovascular System
029
Small intestine, H&E, 40X
030
Mesentery, H&E, 20X (muscular or medium sized arteries and companion veins, tunica intima, internal elastic lamina, tunica media, tunica adventitia).
036
Aorta , stained for elastin, 20X (extensive elastin in wall).
040
Trachea, H&E, 40X (small arteries and veins).
042
Mesentery H&E, 40X
088
Aorta, H&E, 20X (extensive elastin in wall).
092
Muscular or medium sized artery and companion vein, H&E, 20X.
092F
Muscular or medium sized artery and companion vein, Masson stain, 20X.
093
Mesentery H&E, 40X
095
Small arteries and veins, H&E, 20X.
095M
Small arteries and veins, Masson stain, 40X.
098-1
Right heart wall, H&E, 40X (heart wall, ventricle, atrium, atrioventricular valve, chorda tendinae, capillaries in heart muscle).
098N
Right heart wall, Masson, 40X (heart wall, ventricle, atrium, atrioventricular valve, capillaries in heart muscle, coronary artery).
099
Heart, interventricular septum, H&E, 20X (septum, aortic valve, AV valve, chorda tendinae, cardiac skeleton).
099HM
Heart, interventricular septum, Mallory stain, 20X (septum, aortic valve, AV valve, chorda tendinae, Purkinje fibers, cardiac skeleton, atrioventricular bundle of His).
099M
Heart, interventricular septum, Mallory stain, 20X (septum, wall of aorta, aortic valve, AV valve, chorda tendinae, Purkinje fibers, cardiac skeleton, atrioventricular bundle of His).
100HE
Heart wall and aortic valve, H&E, 20X (ventricle, aortic valve, aorta).
100HM
Heart wall and aortic valve, Masson, 40X (ventricle, aortic valve, aorta wall, Purkinje cells).
100W
Heart wall and aortic valve, Aldehyde fuchsin stain, 20X (ventricle, aortic valve, aorta, elastin stain).
102HE
Heart, ventricle, aortic valve H&E, 40X (capillaries in heart muscle).
303
Artery & vein, Verhoeff stain, 40X
304
Femoral artery & vein, canine, von Gieson stain, 40X
305
Heart ventricle, H&E, 40X
Drexel slide MCP35
Inferior Vena Cava
096
Elastic Artery: Note the alternating layers of connective tissue and smooth muscle cells in the media. The junction between the intima and media is difficult to identify!
097
Muscular Artery: Note that the intima in this type of artery consists of only the endothelium. Note also, the obvious internal elastic lamina, the paucity of elastic components within the media and the arrangement of smooth muscle cells.
098
Small Vein: In this wall of a vein, the tunica intima (endothelium), tunica media (3 layers of smooth muscle and interspersed elastic fibers) and a portion of tunica adventitia (collagen fibrils) are clearly recognized.
101
Arteriole: Note that the media in an arteriole consists of only one or two layers of smooth muscle cells. An adventitia may not be present. CAUTION: Although this arteriole contains a complete, albeit thin, internal elastic membrane, many arterioles do not.
114
Continuous Capillary: Note abundance of micropinocytotic vesicles.
119
Fenestrated Capillary: Note the diaphragms within the fenestrations.

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