This collection is curated by Michael Hortsch, Ph.D. If you have questions or comments regarding the University of Michigan virtual slide collection, please contact Dr. Hortsch at hortsch at umich.edu.
Virtual EM Micrograph List
View other topics
Bone and Bone Formation
Cell Biology for the Histologist
Central Nervous System
Female Reproductive System
Introduction to Histology Stains
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Virtual Electron Micrograph Slide List for Histology Course
|Glomerulus: Study the architecture of the glomerulus in this section of renal corpuscle. Review the organization and function of the glomerular endothelium, basement membrane and the podocytes. (The vascular pole is included in the plane of section, but not the urinary pole. The juxtaglomerular cells are secretory cells, derived from smooth muscle cells of the afferent arteriole. The macula densa shown here is cut in tangential section passing only through its wall and does not include the lumen (the rest of the tubule is out of the plane of section). You can at least see the closely-packed nuclei that are characteristic of this modified portion of the distal tubule.
|Glomerulus Detail: Review the components of the glomerular filtration barrier and note that podocytes and their foot processes (pedicels) form the visceral layer of the Bowman’s capsule.
|Proximal Convoluted Tubule (cross section): Note the brush border, composed of closely packed microvilli. Note the numerous mitochondria, in association with basal infoldings of the plasma membrane. Lateral cell membranes are not clearly visible because of extensive interdigitation of neighboring cells.
|Distal Convoluted Tubule: Compare the distal convoluted tubule shown here with the proximal tubule seen in the previous micrograph. Note that, like the epithelial cells of the proximal convoluted tubule, these there are also abundant mitochondria (which you would expect since these cells are involved in the active transport of sodium). However, there are very few microvilli.
|Loop of Henle: Note the abrupt transition of the epithelium lining thin segment to thick segment of the loop of Henle.
|Papillary Collecting Duct (Duct of Bellini, cross section): The cells of the collecting duct grow taller as the duct approaches the renal papilla.
|Urinary Bladder – Transitional Epithelium: The wall of the urinary bladder contains 3 layers of somewhat irregularly arranged smooth muscle.